Haga Y, Shoji H, Oguro K, Mori S, Kawai T, Shinoda S, Masuzawa T, Saito K
Department of Surgical Neurology, Jichi Medical School, Tochigi, Japan.
Neurol Med Chir (Tokyo). 1997 Jul;37(7):551-5. doi: 10.2176/nmc.37.551.
A 15-year-old girl presented with a rare intracerebral schwannoma manifesting as epileptic seizure. Computed tomography, magnetic resonance imaging, and cerebral angiography showed a right parietooccipital lobe tumor. The preoperative diagnosis was malignant glioma, but immunohistochemical and ultrastructural examinations showed the tumor was indistinguishable from peripheral schwannoma. Only 29 cases of schwannomas not related to the cranial nerve have been reported, mostly in children and young adults. The origin appears to be ectopic or perivascular elements in the brain. Such intracerebral schwannomas can be classified according to origins into intra-axial, periventricular, dural attachment, and other types.
一名15岁女孩因罕见的脑内神经鞘瘤出现癫痫发作。计算机断层扫描、磁共振成像和脑血管造影显示右侧顶枕叶有肿瘤。术前诊断为恶性胶质瘤,但免疫组织化学和超微结构检查显示该肿瘤与周围神经鞘瘤无法区分。据报道,与颅神经无关的神经鞘瘤仅有29例,大多发生于儿童和年轻人。其起源似乎是脑内的异位或血管周围成分。此类脑内神经鞘瘤可根据起源分为轴内型、脑室周围型、硬脑膜附着型和其他类型。