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抽动秽语综合征和强迫症中的强迫症状：按诊断和家族史的差异

Obsessive compulsive symptoms in Gilles de la Tourette syndrome and obsessive compulsive disorder: differences by diagnosis and family history.

作者信息

Eapen V, Robertson M M, Alsobrook J P, Pauls D L

机构信息

Department of Psychiatry, University of London, United Kingdom.

出版信息

Am J Med Genet. 1997 Jul 25;74(4):432-8. doi: 10.1002/(sici)1096-8628(19970725)74:4<432::aid-ajmg15>3.0.co;2-j.

DOI:10.1002/(sici)1096-8628(19970725)74:4<432::aid-ajmg15>3.0.co;2-j
PMID:9259380
Abstract

The distribution of obsessive compulsive symptoms was compared in 16 individuals with primary obsessive compulsive disorder (OCD) and 16 individuals with Gilles de la Tourette syndrome (GTS) and associated obsessive compulsive behaviors (OCB). The two groups showed significant differences in the distribution of OC symptomatology. Furthermore, those OCD probands who shared a similar symptom profile with GTS individuals all had a positive family history of OCD. All of the other OCD probands were isolated cases. Implications of this finding on the etiology and pathogenesis of the two disorders are discussed.

摘要

比较了16例原发性强迫症（OCD）患者和16例患有 Gilles de la Tourette 综合征（GTS）及相关强迫行为（OCB）患者的强迫症状分布情况。两组在强迫症状学分布上存在显著差异。此外，那些与GTS患者具有相似症状特征的OCD先证者均有OCD的阳性家族史。所有其他OCD先证者均为散发病例。讨论了这一发现对两种疾病病因和发病机制的意义。

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