信号酶：潜力无限。

Signalling enzymes: bursting with potential.

作者信息

Braselmann S, Palmer T M, Cook S J

机构信息

ONYX Pharmaceuticals, Richmond, California 94806, USA.

出版信息

Curr Biol. 1997 Aug 1;7(8):R470-3. doi: 10.1016/s0960-9822(06)00239-9.

DOI:10.1016/s0960-9822(06)00239-9

PMID:9259544

Abstract

A newly identified form of phosphoinositide 3-kinase is regulated by G beta gamma subunits and is particularly abundant in phagocytic leukocytes. It is likely to be intimately involved in the process by which inflammatory signals regulate phagocyte activation and is a potential target for new anti-inflammatory drugs.

摘要

一种新发现的磷酸肌醇3激酶形式受Gβγ亚基调控，在吞噬性白细胞中含量尤其丰富。它可能密切参与炎症信号调节吞噬细胞活化的过程，是新型抗炎药物的潜在靶点。