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鞍内及鞍上生殖细胞瘤

Intrasellar and suprasellar germinoma.

作者信息

Lin C L, Loh J K, Howng S L

机构信息

Department of Neurosurgery, Kaohsiung Medical College, Taiwan, Republic of China.

出版信息

Kaohsiung J Med Sci. 1997 Jul;13(7):462-6.

PMID:9260468
Abstract

A 15-year-old male was admitted to our hospital with diabetes insipidus, headache and bitemporal hemianopia and a computed tomogram (CT) revealed an intra- and suprasellar tumor. Differential diagnosis between large intra- and suprasellar germinoma and pituitary adenomas is quite difficult based on CT. After comparing our case with past literature of reported cases of intrasellar and suprasellar germinoma, we found that an enhanced mass posterior to the pituitary gland on the midsagittal magnetic resonance imaging (MRI) and absence of the high signal intensity of the posterior lobe on T1-weighted MRI in patients with diabetes insipidus indicated germinoma rather than a pituitary adenoma. Transphenoid approach and appropriate radiotherapeutic management were administered with a good result.

摘要

一名15岁男性因尿崩症、头痛和双颞侧偏盲入院,计算机断层扫描(CT)显示鞍内及鞍上有肿瘤。基于CT鉴别鞍内及鞍上大型生殖细胞瘤和垂体腺瘤相当困难。将我们的病例与既往鞍内及鞍上生殖细胞瘤报告病例的文献进行比较后,我们发现,矢状位磁共振成像(MRI)上垂体后方强化肿块以及尿崩症患者T1加权MRI上垂体后叶无高信号强度提示为生殖细胞瘤而非垂体腺瘤。采用经蝶窦入路并进行了适当的放射治疗,效果良好。

相似文献

1
Intrasellar and suprasellar germinoma.鞍内及鞍上生殖细胞瘤
Kaohsiung J Med Sci. 1997 Jul;13(7):462-6.
2
[A case of intrasellar pure germinoma].[一例鞍内纯生殖细胞瘤]
No Shinkei Geka. 2000 Mar;28(3):263-7.
3
Intra- and suprasellar germinoma mimicking a pituitary adenoma--case report.鞍内及鞍上生殖细胞瘤酷似垂体腺瘤——病例报告
Neurol Med Chir (Tokyo). 1995 Feb;35(2):96-9. doi: 10.2176/nmc.35.96.
4
Suprasellar germ cell tumor with subarachnoid seeding MRI and MR spectroscopy findings.
Clin Imaging. 2004 Nov-Dec;28(6):404-7. doi: 10.1016/S0899-7071(03)00315-2.
5
Suprasellar germinomas in childhood and adolescence: diagnostic pitfalls.儿童及青少年鞍上生殖细胞瘤:诊断陷阱
J Pediatr Endocrinol Metab. 1998 Nov-Dec;11(6):693-7. doi: 10.1515/jpem.1998.11.6.693.
6
[A case of intrasellar and suprasellar meningioma with hypopituitarism].[一例伴有垂体功能减退的鞍内及鞍上脑膜瘤]
No Shinkei Geka. 1990 Jul;18(7):637-42.
7
[A Case of Suprasellar Germinoma that Spontaneously Regressed before Endoscopic Biopsy].
No Shinkei Geka. 2016 Oct;44(10):851-855. doi: 10.11477/mf.1436203389.
8
[Double localization of intracranial germinoma. Apropos of a case].[颅内生殖细胞瘤的双重定位。附1例报告]
Neurochirurgie. 1995;41(6):424-8.
9
Thickened pituitary stalk on magnetic resonance imaging in children with central diabetes insipidus.中枢性尿崩症患儿磁共振成像显示垂体柄增粗。
J Clin Endocrinol Metab. 1999 Jun;84(6):1954-60. doi: 10.1210/jcem.84.6.5745.
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[Diagnosis and treatment of sellar germinoma].[鞍区生殖细胞瘤的诊断与治疗]
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2003 Jun;25(3):350-3.

引用本文的文献

1
Sellar and suprasellar mixed germ cell tumor mimicking a pituitary adenoma.鞍内及鞍上混合性生殖细胞瘤,类似于垂体腺瘤。
Pituitary. 2011 Dec;14(4):345-50. doi: 10.1007/s11102-008-0161-z.