无法切除的胰腺癌：多模式治疗方法是一种有前景的治疗选择吗？

Unresectable pancreatic cancer: is a multi-modality approach a promising therapeutical alternative?

作者信息

Lygidakis N J, Dedemati G, Spenzaris N, Theodoropoulou M

机构信息

Department of Surgery, Athens Medical Center, Athens, Greece.

出版信息

Hepatogastroenterology. 1997 Jul-Aug;44(16):1222-8.

PMID:9261631

Abstract

BACKGROUND/AIMS: The aim of this study was to evaluate the combination of immunochemotherapy and stop-flow upper abdominal chemotherapy in the prolongation of survival in patients with unresectable pancreatic cancer.

METHODOLOGY

Thirty unresectable pancreatic cancer patients were treated with immuno-chemotherapy in combination with stop-flow upper abdominal chemotherapy, in an attempt to improve survival time.

RESULTS

The results obtained in this study indicate that this kind of treatment is feasible, safe and effective for patients suffering from Stage III and IV pancreatic duct carcinoma. Twenty per cent of the patients within this group were able to undergo radical resection and remain alive and free of disease, with a mean survival rate of 16 months.

CONCLUSION

The multi-modality approach used in this study achieved promising results for pancreatic cancer patients and is recommended as a promising therapeutic alternative.

摘要

背景/目的：本研究旨在评估免疫化疗与上腹部阻断化疗联合应用对不可切除胰腺癌患者生存期的延长作用。