Olmedo S B, Nodar F, Chillik C, Chemes H E
Centro de Estudios en Ginecologia y Reproduccion, Buenos Aires, Argentina.
Hum Reprod. 1997 Jul;12(7):1497-9. doi: 10.1093/humrep/12.7.1497.
The present report describes a successful intracytoplasmic sperm injection (ICSI) procedure performed with immotile spermatozoa from a young man with a combination of dysplasia of the fibrous sheath and dynein deficiency, a recently described variant of the immotile cilia syndrome. This methodology provides the only suitable solution for these patients in whom all other assisted fertilization technologies have previously failed, and opens the possibilities for treatment of male infertility due to severe, irreversible sperm defects such as the one reported here.
本报告描述了一例成功的胞浆内单精子注射（ICSI）手术，该手术使用的是一名患有纤维鞘发育异常和动力蛋白缺乏综合征（一种最近发现的不动纤毛综合征变体）的年轻男性的无活力精子。这种方法为所有其他辅助受精技术均告失败的这些患者提供了唯一合适的解决方案，并为治疗因严重、不可逆的精子缺陷（如此处报道的情况）导致的男性不育开辟了可能性。
