DeMeester T R
Department of Surgery, University of Southern California School of Medicine, Los Angeles 90033-4612, USA.
Semin Thorac Cardiovasc Surg. 1997 Jul;9(3):290-301.
Esophageal adenocarcinoma is a highly malignant tumor and, if not diagnosed at an early stage, carries a poor prognosis. Controversy exists over how to manage carcinoma of the esophagus confined to the mucosa and the extent of resection to cure disease that has extended beyond the mucosa. Similarly, there are differing opinions regarding the role of adjuvant chemotherapy and the efficacy of surgical resection for palliation. These issues are discussed as they pertain to the management of adenocarcinoma arising in Barrett's esophagus.
食管腺癌是一种高度恶性的肿瘤，如果不及早诊断，预后较差。对于局限于黏膜层的食管癌如何处理以及对于已超出黏膜层的疾病进行根治性切除的范围，目前存在争议。同样，关于辅助化疗的作用以及手术切除用于缓解症状的疗效也存在不同观点。本文将针对这些与巴雷特食管中发生的腺癌的处理相关的问题进行讨论。
