Caballero Alcántara J, Marchal Escalona C, Padilla León M, Moreno Cerro A, Martínez Tello F J, Leiva Galvis O
Unidad de Urología, Hospital Costa del Sol, Marbella, Málaga.
Actas Urol Esp. 1997 Apr;21(4):361-71.
The study proposes the analysis of the influence of gross, microscopical and clinical pathoanatomical prognostic factors in the survival of patients with RCC through univariance and multivariance statistical analysis, and its global evaluation as a predictive model.
The study involved 218 RCC cases operated on over 20 years, with a mean follow-up of 60 months.
All prognostic factors studied have a significant influence on the survival. When studied jointly, they include separately and in order of significance the metastatic involvement, mitotic index, cava vein involvement, nuclear grade and sarcomatoid histologic pattern. Also, we confirm that considered jointly they conform a valid predictive model.
本研究旨在通过单变量和多变量统计分析，探讨大体、微观和临床病理解剖学预后因素对肾细胞癌（RCC）患者生存的影响，并将其作为预测模型进行整体评估。
本研究纳入了218例在20多年间接受手术治疗的RCC病例，平均随访60个月。
所有研究的预后因素均对生存有显著影响。联合研究时，它们按重要性顺序分别包括转移累及、有丝分裂指数、腔静脉累及、核分级和肉瘤样组织学模式。此外，我们证实联合考虑时它们构成一个有效的预测模型。
