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[缺血性心脏病猝死心肌的形态学及生化改变]

[Morphological and biochemical changes in the myocardium after sudden death from ischemic heart disease].

作者信息

Kapustin A V, Bel'chenko D I, Antonova L A, Domanskiĭ V Iu, Kaĭkova V M

出版信息

Kardiologiia. 1977 Aug;17(8):118-22.

PMID:926554
Abstract

The myocardium was examined in 44 persons who had suddenly died of ischemic heart disease, in 37 who had died of injury, and in 28 who had died of alcohol poisoning. Those with ischemic heart disease had foci of necrosis of the muscle fibers, severe disturbances in microcirculation, changes in the activity of certain myocardial enzymes and in the content of lipids in the myocardium. Biochemical changes similar to these in many respects were revealed in individuals who had died of alcohol poisoning, in view of which alcohol poisoning may be a factor conducive to sudden death in ischemic heart disease.

摘要

对44例因缺血性心脏病突然死亡的患者、37例因损伤死亡的患者以及28例因酒精中毒死亡的患者的心肌进行了检查。患有缺血性心脏病的患者存在肌纤维坏死灶、严重的微循环紊乱、某些心肌酶活性的变化以及心肌脂质含量的变化。在因酒精中毒死亡的个体中也发现了在许多方面与这些相似的生化变化,鉴于此,酒精中毒可能是导致缺血性心脏病猝死的一个因素。

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