Kryzhanovskaia I I, Arshava V P, Popova E V, Kryzhanovskiĭ D G, Erkes E L
Kardiologiia. 1977 Sep;17(9):78-84.
Certain metabolic disorders characterizing disturbances both in neuroendocrine control and in metabolic processes at the cell and tissue levels were revealed in 472 patients with rheumatic heart disease, atherosclerotic cardiosclerosis, and cor pulmonale. The disturbance in the adrenal function was of a dissociated character, manifested by increase in sympathoadrenal and decrease in glucocorticoid activity. The indices of pentosophosphate cycle and erythrocyte and blood serum enzymes studied testify to deep changes in the state of the erythron, marked both by breaks and by adaptation to hypoxia caused by circulatory insufficiency.
在472例风湿性心脏病、动脉粥样硬化性心硬化和肺心病患者中，发现了某些代谢紊乱，这些紊乱表现为神经内分泌控制以及细胞和组织水平的代谢过程均受到干扰。肾上腺功能紊乱具有分离性，表现为交感肾上腺活性增加和糖皮质激素活性降低。所研究的磷酸戊糖循环指标以及红细胞和血清酶表明红细胞状态发生了深刻变化，这既表现为中断，也表现为对循环功能不全所致缺氧的适应。
