Cerebral amyloid angiopathy with extensive mineralization.

Cerebral amyloid angiopathy (CAA, congophilic angiopathy) occurs with aging, Alzheimer's disease, and certain rare familial syndromes. It is an important risk factor for spontaneous intracerebral hemorrhage. In addition to the accumulation of amyloid within the walls of cortical and leptomeningeal blood vessels, CAA is often accompanied by other vascular changes (CAA-associated vasculopathies, CAA-AV). This case report describes the unusual finding of extensive vascular mineralization with CAA, a rare form of CAA-AV which was detected during life.