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脊柱包虫病:来自土耳其的一项调查研究

Hydatid disease of the spine: a survey study from Turkey.

作者信息

Turgut M

机构信息

Dept. of Neurosurgery, Adnan Menderes University School of Medicine, Aydin, Turkey.

出版信息

Infection. 1997 Jul-Aug;25(4):221-6. doi: 10.1007/BF01713148.

DOI:10.1007/BF01713148
PMID:9266261
Abstract

Spinal hydatid disease is rare, even in rural areas where echinococcosis is endemic. Although the liver and lungs are commonly involved, spinal hydatid disease, either primary or secondary, represents an uncommon but significant manifestation of the disease. This survey study reviews 28 reports of spinal hydatid disease from Turkey during the past 5 decades. Only 14 patients also had pulmonary or some other organ infestation. The cysts affecting the spine were commonly in the thoracic region. Most patients had intraspinal extradural hydatid-cysts associated with vertebral involvement. The presenting symptoms were mostly atypical, and it was interesting that most of the patients were misdiagnosed preoperatively as Pott's disease during the first decades, suggesting that new imaging techniques such as CT and MRI are the diagnostic procedures of choice for this disease. Surgery remains the best therapy for spinal hydatid disease, although adjuvant antihelminthic therapy may be necessary. There were only 15 cases of recurrence (18%); surgical intervention was palliative in all these patients and it was followed by chemotherapy. Operative mortality was very low (two patients died in the early postoperative period) and there were no complications related to treatment with antihelminthic drugs. The study indicates that hydatid disease should be considered in the differential diagnosis when radiological findings suggest spinal infections or tumors, and that surgical decompression in association with chemotherapy is the treatment of choice.

摘要

脊髓包虫病很罕见,即便在棘球蚴病流行的农村地区也是如此。虽然肝脏和肺脏是该病常见的受累部位,但原发性或继发性脊髓包虫病是该疾病一种不常见却很重要的表现形式。这项调查研究回顾了过去50年间土耳其28例脊髓包虫病的报告。仅有14例患者还伴有肺部或其他器官感染。影响脊柱的囊肿常见于胸段。大多数患者有椎管内硬膜外包虫囊肿并伴有椎体受累。呈现的症状大多不典型,有意思的是,在最初几十年里大多数患者术前被误诊为脊柱结核,这表明CT和MRI等新的成像技术是诊断该病的首选检查方法。手术仍然是脊髓包虫病的最佳治疗方法,不过可能需要辅助抗蠕虫治疗。仅有15例复发(18%);对所有这些患者手术干预都是姑息性的,随后进行化疗。手术死亡率非常低(2例患者在术后早期死亡),且没有与抗蠕虫药物治疗相关的并发症。该研究表明,当影像学检查结果提示脊髓感染或肿瘤时,鉴别诊断中应考虑包虫病,手术减压联合化疗是首选治疗方法。

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1
Hydatid disease of the spine: a survey study from Turkey.脊柱包虫病:来自土耳其的一项调查研究
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2
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A rare case of recurrent primary dumbbell-shaped spinal hydatidosis.一例罕见的复发性原发性哑铃形脊柱包虫病。
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