Lerche W, Maslo K H
Klin Monbl Augenheilkd. 1977 Sep;171(3):450-8.
Proliferations fo the retinal pigment epithelium over malignant malanoms of the coroid were examined in the following regions: 1. at the posterior pole, 2. in the equator region, 3. in the ora region. The pigment epithelial cells exist in each proliferation in a differently marked pattern of mono- and double layers. Furthermore the proliferations show a varying amount and localisation of a fine fibrillar substance. The majority of the proliferated pigment epithelial cells at the posterior pole are loosely arranged to mono and double layers. Fine fibrillar substance occurs only adjacent to the mono-layers. The proliferation at the equator has a more distinct layering of the cells. The fine fibrillar substance is mainly located between the two layers of double layered cell complexes. The proloferation in the ora-region is characterised by numerous flat mono- and double layers which are embedded in fine fibrillar substance.