Effect of autoclaving and physical structure of diets on their utilization by mice.

A pelleted and 2 expanded rodent diets were autoclaved at 121 degrees C for 20 minutes, and fed to DBA/1 and LACA strains of mice. Reproduction was not significantly different on any diet and autoclaving had no effect other than increasing the intervals between litters. However, apparent food consumption was greater and efficiency of food utilization (expressed as young weaned/diet consumed) was poorer in mice fed pelleted diets. Diet had no significant effect on growth, but food wastage and consequently apparent food consumption were less and food utilization more efficient when expanded diets were fed. In addition, true food consumption was lower and food conversion more efficient. Autoclaving had little effect on expanded diets but caused a significant reduction in wastage and in apparent and true consumption of the pelleted diet, perhaps because of increased hardness.