Hume E B, Willcox M D
Cooperative Research Centre for Eye Research and Technology, University of New South Wales, Sydney, Australia.
Aust N Z J Ophthalmol. 1997 May;25 Suppl 1:S39-41. doi: 10.1111/j.1442-9071.1997.tb01753.x.
The adhesion to hydrogel contact lenses and growth of Serratia marcescens on artificial tear fluid (ATF) soaked lenses was investigated. Results indicated that a corneal ulcer isolate adhered more avidly to lenses; ATF increased adhesion for all strains tested. The contact lens induced acute red eye (CLARE) isolate adhered poorly, however, it grew to a larger extent on ATF-coated lenses. The ability of the corneal ulcer isolate to adhere to lenses may be an important factor in its pathogenicity whereas the ability of the CLARE isolate to grow on the lens in the presence of antimicrobial tear proteins may be important in the development of inflammation.
研究了粘质沙雷氏菌在水凝胶隐形眼镜上的黏附情况以及在浸泡于人工泪液(ATF)的隐形眼镜上的生长情况。结果表明,一种角膜溃疡分离株对隐形眼镜的黏附更为强烈;ATF增加了所有测试菌株的黏附。然而,隐形眼镜诱发的急性红眼(CLARE)分离株黏附性较差,但其在涂有ATF的隐形眼镜上生长得更为旺盛。角膜溃疡分离株黏附于隐形眼镜的能力可能是其致病性的一个重要因素,而CLARE分离株在存在抗菌泪液蛋白的情况下在隐形眼镜上生长的能力可能在炎症发展中起重要作用。