Rose K A, Levick W R, Burke W
Visual Neurosciences Unit, John Curtin School of Medical Research, Australian National University, Canberra, Australia.
Aust N Z J Ophthalmol. 1997 May;25 Suppl 1:S61-3. doi: 10.1111/j.1442-9071.1997.tb01759.x.
In the cat optic nerve a lesion was induced by brief application of pressure. It selectively blocked impulse conduction in large diameter fibres of the retinal ganglion cells. Electrophysiological examination of single optic axons several weeks later demonstrated a gross alteration of the visual properties of the affected BT/Y ganglion cells. It is suggested that the alteration of receptive field properties may reflect the cellular and dendritic response to distant focal injury of the axon.
