Localization of D1 dopamine receptors in the chicken retina.

PURPOSE

The localization of dopamine D1 receptors (DIR) in the chicken retina was examined using an anti-human DIR monoclonal antibody and PAP techniques.

RESULTS

A clear band of staining was seen in the outer plexiform layer, as well as cellular staining in the outer-most part of the inner nuclear layer, probably in a subset of horizontal cells. Many different amacrine cell bodies were labelled in the inner one-third of the inner nuclear layer. There was also extensive staining in the inner plexiform layer, which showed some striation. Occasional labelled ganglion cells were also detected.

CONCLUSION

Localization of D1-dopamine receptors has been shown in the chicken retina.