Barraquer J I, Gomez M L
Barraquer Institute of America, Santa fe de Bogota, Colombia.
J Refract Surg. 1997 Jul-Aug;13(4):342-8. doi: 10.3928/1081-597X-19970701-09.
To assess the efficacy, stability, and safety of Permalens hydrogel intracorneal lenses for the correction of spherical ametropia 6 years after implantation.
Implantation of intracorneal hydrogel lenses was performed by the same surgeon (JIBM) in five aphakic and five high myopic eyes. The lens closet to corneal vertex refraction was used. Refractive outcomes, keratometry, keratography, endothelial cell count, and corneal topography were studied.
Corneal tolerance to the hydrogel implants was maintained throughout for 6 years with no alteration in endothelial cell count. All myopic eyes showed regression of achieved correction. The aphakic eyes showed no statistically significant difference between the results at 1 month and those obtained at 1 and 6 years.
Hyrdogel intracorneal lenses are well tolerated and the refractive results are stable in aphakic patients. They may be considered when intraocular lenses cannot be placed in aphakic patients, but are not now in clinical use.
评估Permalens水凝胶角膜内透镜植入6年后矫正球面屈光不正的有效性、稳定性和安全性。
同一位外科医生（JIBM）在5只无晶状体眼和5只高度近视眼眼中植入角膜内水凝胶透镜。使用最接近角膜顶点屈光力的透镜。研究了屈光结果、角膜曲率测量、角膜地形图、内皮细胞计数和角膜地形图。
在整个6年期间，角膜对水凝胶植入物的耐受性良好，内皮细胞计数无变化。所有近视眼的矫正度数均出现回退。无晶状体眼在1个月时的结果与1年和6年时的结果之间无统计学显著差异。
水凝胶角膜内透镜耐受性良好，在无晶状体患者中屈光结果稳定。当无晶状体患者无法植入人工晶状体时可考虑使用，但目前尚未用于临床。
