Mens L H, Oostendorp T F, Hombergen G C, den Broek P
Department of Otorhinolaryngology, University Hospital Nijmegen, The Netherlands.
Ann Otol Rhinol Laryngol. 1997 Aug;106(8):653-6. doi: 10.1177/000348949710600807.
Hyaluronic acid (Healon), oxycellulose (hydroxypropyl methylcellulose), and glycerin are lubricants used in cochlear implant surgery for atraumatic deep insertion of the electrode array into the scala tympani. The electrical impedances of these three lubricants were measured to assess possible effects on intraoperative evoked response measurements, such as the electrically evoked stapedius reflex and auditory brain stem response. The impedances of hyaluronic acid, oxycellulose, and saline were very similar and independent of frequency (20 Hz to 1 MHz). Glycerin had an excessively high impedance at low frequencies. A film of hyaluronic acid or oxycellulose around the electrode array immersed in saline did not have any measurable effect on the impedance; a film of glycerin resulted in a strongly reactive polarized layer. However, neither the far-field current spread nor the impedance between stimulated electrodes was affected by any of the lubricants applied as a thin film. This suggests that none of these lubricants affect intraoperative responses, when applied as a thin film.
透明质酸（Healon）、氧化纤维素（羟丙基甲基纤维素）和甘油是用于人工耳蜗植入手术的润滑剂，可将电极阵列无创伤地深插入鼓阶。测量了这三种润滑剂的电阻抗，以评估其对术中诱发反应测量可能产生的影响，如电诱发镫骨肌反射和听觉脑干反应。透明质酸、氧化纤维素和生理盐水的电阻抗非常相似，且与频率（20赫兹至1兆赫）无关。甘油在低频时具有过高的电阻抗。浸没在盐水中的电极阵列周围的透明质酸或氧化纤维素薄膜对电阻抗没有任何可测量的影响；甘油薄膜会导致形成强反应性极化层。然而，远场电流扩散以及刺激电极之间的电阻抗均不受作为薄膜应用的任何一种润滑剂的影响。这表明，当作为薄膜应用时，这些润滑剂均不会影响术中反应。
