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淡水鲑鱼养殖中的疫苗接种策略。

Vaccination strategies in freshwater salmonid aquaculture.

作者信息

Larsen J L, Pedersen K

机构信息

Department of Veterinary Microbiology, Royal Veterinary and Agricultural University, Copenhagen, Denmark.

出版信息

Dev Biol Stand. 1997;90:391-400.

PMID:9270868
Abstract

The focus of this chapter is antibacterial vaccines. The main salmonid species in freshwater aquaculture is the rainbow trout. Other salmonid species are produced on a limited scale. The most important bacterial fish diseases in European freshwater aquaculture are the rainbow trout fry syndrome-RTFS-(Flavobacterium psychrophilum) and enteric redmouth disease-ERM-(Yersinia ruckeri) which are widespread and cause serious epizootics, while furunculosis (Aeromonas salmonicida) is endemic, only giving overt disease under extremely stressing conditions. In the hatchery, there is a need for vaccination against RTFS (not commercially available) and ERM; in the ponds it is urgent to vaccinate against ERM, while the importance of furunculosis vaccination is not clear. The fish for ongrowing in saltwater should be vaccinated against ERM, furunculosis and vibriosis. Commercial vaccines are available against these diseases, either as single component or combination vaccines for immersion and injection-and oral vaccines are under registration. Hitherto, there has not been much strategic research on vaccination in freshwater; however recent results suggest that with the regime of vaccines available (and soon available), fish should be vaccinated with an ERM immersion vaccine in the hatchery approximately four weeks before transfer to the ponds. To cover the growth period in fresh water an oral booster should be given two to three months later. There is a need for development and research in strategic use of an RTFS and a furunculosis vaccine in freshwater aquaculture.

摘要

本章的重点是抗菌疫苗。淡水养殖中主要的鲑科鱼类是虹鳟。其他鲑科鱼类的产量有限。欧洲淡水养殖中最重要的细菌性鱼类疾病是虹鳟鱼苗综合征(RTFS,嗜冷黄杆菌)和肠红嘴病(ERM,鲁氏耶尔森菌),它们广泛传播并引发严重的流行病,而疖疮病(杀鲑气单胞菌)呈地方性流行,仅在极端应激条件下才会引发明显疾病。在孵化场,需要针对RTFS(无商业疫苗)和ERM进行疫苗接种;在池塘中,迫切需要针对ERM进行疫苗接种,而疖疮病疫苗接种的重要性尚不清楚。用于海水养殖育肥的鱼应接种针对ERM、疖疮病和弧菌病的疫苗。有针对这些疾病的商业疫苗,有单组分疫苗或用于浸浴和注射的联合疫苗,口服疫苗也正在注册中。迄今为止,淡水养殖疫苗接种方面的战略研究不多;然而,最近的结果表明,根据现有的(以及即将推出的)疫苗接种方案,鱼应在转移到池塘前约四周在孵化场接种ERM浸浴疫苗。为了覆盖淡水养殖期,应在两到三个月后给予口服加强疫苗。在淡水养殖中,需要对RTFS和疖疮病疫苗的战略使用进行开发和研究。

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