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无需任何额外设备的内镜圈套器食管黏膜切除术:一种切除平坦型早期食管癌的简单技术。

Endoscopic snare mucosectomy in the esophagus without any additional equipment: a simple technique for resection of flat early cancer.

作者信息

Soehendra N, Binmoeller K F, Bohnacker S, Seitz U, Brand B, Thonke F, Gurakuqi G

机构信息

Dept. of Endoscopic Surgery, University Hospital Eppendorf, Hamburg, Germany.

出版信息

Endoscopy. 1997 Jun;29(5):380-3. doi: 10.1055/s-2007-1004219.

Abstract

BACKGROUND AND STUDY AIMS

Endoscopic mucosal resection of early esophageal cancer has increasingly proved to be an effective treatment modality, especially if the tumor has not invaded the muscularis mucosae. Different techniques have been introduced, using an overtube, double-channel endoscope, or suction cap. We have not found that these devices are required for snare resection in the esophagus.

PATIENTS AND METHODS

Over a period of two years (1994-1996), seven patients (five men and two women, age range 59-88) with early esophageal cancer defined by endosonography (3 cm or less in size, limited to the submucosal layer) were treated using a simplified technique of endoscopic snare resection using a monopolar diathermic polypectomy snare made of monofilament steel wire. The snare was positioned around the lesion, and then closed while pressing the snare against the mucosa and applying suction to draw the lesion into the snare. Pure coagulation current was used for resection. If necessary, a piecemeal technique was used to achieve complete removal.

RESULTS

Complete removal was achieved in one session in all seven cases. No complications were observed. Two patients underwent radical surgery with no tumor remnant or metastatic lymph node in the resected specimen. All patients have remained free of recurrence during a median follow-up period of seven months (range 3-22 months). Two patients died of cardiovascular disease four and eight months after endoscopic mucosal resection.

CONCLUSION

Small early esophageal cancer can be safely removed with a simplified method of endoscopic snare resection using a standard monofilament polypectomy snare.

摘要

背景与研究目的

内镜下黏膜切除术已越来越多地被证明是治疗早期食管癌的一种有效方法,尤其是当肿瘤尚未侵犯黏膜肌层时。已引入了不同的技术,使用外套管、双通道内镜或吸引帽。我们发现食管圈套切除并不需要这些装置。

患者与方法

在两年期间(1994 - 1996年),对7例经超声内镜确诊为早期食管癌(大小3cm或更小,局限于黏膜下层)的患者(5例男性,2例女性,年龄范围59 - 88岁)采用简化的内镜圈套切除技术进行治疗,该技术使用由单丝钢丝制成的单极电凝息肉切除圈套器。将圈套器置于病变周围,然后在将圈套器压向黏膜并施加吸引以将病变吸入圈套器的同时关闭圈套器。使用纯凝固电流进行切除。如有必要,采用分块切除技术以实现完全切除。

结果

所有7例患者均在一次手术中实现了完全切除。未观察到并发症。2例患者接受了根治性手术,切除标本中无肿瘤残留或转移淋巴结。所有患者在中位随访期7个月(范围3 - 22个月)内均无复发。2例患者在内镜黏膜切除术后4个月和8个月死于心血管疾病。

结论

使用标准的单丝息肉切除圈套器,通过简化的内镜圈套切除方法可以安全地切除小型早期食管癌。

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