制备（E）-4-羟基-2-烯醛的简便通用方法。
Facile and general method for preparation of (E)-4-hydroxy-2-alkenals.
作者信息
Sugamoto K, Matsushita Y, Matsui T
机构信息
Department of Materials Science, Faculty of Engineering, Miyazaki University, Japan.
出版信息
Lipids. 1997 Aug;32(8):903-5. doi: 10.1007/s11745-997-0116-y.
PMID:9270984
Abstract
A facile one-pot synthesis of (E)-4-hydroxy-2-alkenals such as (E)-4-hydroxy-2-nonenal, (E)-4-hydroxy-2-heptenal, and (E)-4-hydroxy-2-hexenal was achieved from the corresponding (2E,4E)-2,4-alkadienals by reduction-oxygenation with molecular oxygen and triethylsilane in the presence of cobalt(II) porphyrin as a catalyst followed by treatment with trimethylphosphite.
摘要
通过在钴（II）卟啉作为催化剂存在下，用分子氧和三乙基硅烷进行还原-氧化反应，然后用亚磷酸三甲酯处理，由相应的（2E，4E）-2，4-链二烯醛简便地一锅合成了（E）-4-羟基-2-烯醛，如（E）-4-羟基-2-壬烯醛、（E）-4-羟基-2-庚烯醛和（E）-4-羟基-2-己烯醛。
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