基于吲哚醌的新型生物还原抗癌剂。
Novel bioreductive anticancer agents based on indolequinones.
作者信息
Moody C J, Swann E
机构信息
Department of Chemistry, University of Exeter, Devon, UK.
出版信息
Farmaco. 1997 May;52(5):271-9.
PMID:9273997
Abstract
The background to bioreductive drugs based on indolequinones is surveyed, and the development of novel cyclopropamitosenes as potent anticancer agents is reviewed. Thiazolylindoles were also investigated as potential inhibitors of topoisomerase II.
摘要
综述了基于吲哚醌的生物还原药物的背景，并对新型环丙胺嗪作为强效抗癌剂的发展进行了综述。噻唑基吲哚也作为拓扑异构酶II的潜在抑制剂进行了研究。
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