线粒体生化研究中常用的某些化合物对单胺氧化酶活性的影响。
The influence of some compounds commonly used in biochemical studies of mitochondria on the activity of monoamine oxidases.
作者信息
Zemskova M A, Axenova L N, Medvedev A E
机构信息
Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Moscow, Russia.
出版信息
Biochemistry (Mosc). 1997 Apr;62(4):448-9.
PMID:9275283
Abstract
It was previously described that low concentrations of sodium azide monoamine oxidase (MAO) B assayed by spectrophotometric measurement of benzaldehyde or by hydrogen peroxide accumulation. We failed to confirm this effect using radiometric determination of MAO activity. Tris or dinitrophenol inhibit MAO. The data suggest that some "regulatory effects" depend on the assay of MAO activity.
摘要
先前曾有描述称，通过分光光度法测量苯甲醛或通过过氧化氢积累来测定低浓度叠氮化钠单胺氧化酶（MAO）B。我们未能通过放射性测定MAO活性来证实这种效应。Tris或二硝基苯酚会抑制MAO。数据表明，一些“调节作用”取决于MAO活性的测定方法。
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