Li M, Liu Z
School of Stomatology, Shanghai Second Medical University.
Zhonghua Kou Qiang Yi Xue Za Zhi. 1996 Jan;31(1):9-11.
In this study, the effects of lipoteichoic acid (LTA) and calcium on adherence of oral streptococci in vitro were investigated. The results revealed that the adherence of streptococcus sobrinus to a glass surface was increased by the addition of calcium, in the condition of the same calcium ion concentration, LTA inhibited adherence, suggesting that LTA and the bacterial cell surface LTA competed for the same site of calcium ion, providing some evidence to support calcium-bridging theory. The result also showed that calcium ion not only influenced sucrose-independent adherence, but also infulenced sucrose-dependent adherence. The effect of calcium ion on the adherence has a threshold, over which the adherence was reduced.
在本研究中,研究了脂磷壁酸(LTA)和钙对口腔链球菌体外黏附的影响。结果显示,在相同钙离子浓度条件下,添加钙可增加远缘链球菌对玻璃表面的黏附,而LTA抑制黏附,这表明LTA与细菌细胞表面的LTA竞争钙离子的同一结合位点,为支持钙桥理论提供了一些证据。结果还表明,钙离子不仅影响非蔗糖依赖性黏附,还影响蔗糖依赖性黏附。钙离子对黏附的影响存在一个阈值,超过该阈值黏附会降低。