Guiney M J, Smith J G, Worotniuk V, Ngan S, Blakey D
Peter MacCallum Cancer Institute, Melbourne, Victoria, Australia.
Int J Radiat Oncol Biol Phys. 1997 Jul 15;38(5):1019-25. doi: 10.1016/s0360-3016(97)00315-5.
To assess the success of external beam radiation treatment in the management of loco-regional recurrence of rectosigmoid cancer.
A retrospective analysis of 135 patients with locally recurrent rectosigmoid cancer presenting to Peter MacCallum Cancer Institute between January 1981 and December 1990 was undertaken. Patients were treated with three different dose ranges of radiotherapy: 50-60 Gy ("Radical" group), 45 Gy ("High-dose palliative" group), and <45 Gy ("Low-dose palliative" group). Symptomatic response rates and overall survival for each group were determined.
Symptomatic response rates of 85, 81, and 56% were achieved in the radical, high-dose palliative, and low-dose palliative groups, respectively. Estimated median survival times were 17.9, 14.8, and 9.1 months for the radical, high-dose palliative, and low-dose palliative groups, respectively.
评估体外放射治疗在乙状结肠癌局部区域复发治疗中的疗效。
对1981年1月至1990年12月间就诊于彼得·麦卡勒姆癌症研究所的135例局部复发乙状结肠癌患者进行回顾性分析。患者接受了三种不同剂量范围的放射治疗：50 - 60 Gy（“根治性”组）、45 Gy（“高剂量姑息性”组）和<45 Gy（“低剂量姑息性”组）。确定了每组的症状缓解率和总生存率。
根治性组、高剂量姑息性组和低剂量姑息性组的症状缓解率分别为85%、81%和56%。根治性组、高剂量姑息性组和低剂量姑息性组的估计中位生存时间分别为17.9个月、14.8个月和9.1个月。
