Cavalieri U, Casale G, Guaita A
Minerva Med. 1977 Oct 13;68(48):3325-30.
The effects of intake of potassium salts for 21-28 days on the glucose tolerance of 10 elderly subjects with clear diabetes were examined by means of the Tolbutamide test (TT) and the i.v. glucose tolerance test (IVGTT). Improvement in tolerance, to the extent of a reduction in glycaemic levels and better coefficients, was observed in all values of the two tests and in basal glycaemia values, with constantly significant differences at statistical examination. In a group of 4 cases in which Tolbutamide treatment was suspended for the same period, this improvement in the Tolbutamide Test was not observed. With this second confirmation of the initial hypothesis, the pathogenetic significance and biological relevance of potassium depletion in senile diabetes and generally, in the ageing process, are discussed.
通过甲苯磺丁脲试验（TT）和静脉葡萄糖耐量试验（IVGTT），研究了21 - 28天摄入钾盐对10例明确患有糖尿病的老年受试者葡萄糖耐量的影响。在两项试验的所有值以及基础血糖值中均观察到耐受性有所改善，表现为血糖水平降低和系数更好，在统计学检验中差异始终具有显著性。在一组4例在同一时期暂停甲苯磺丁脲治疗的病例中，未观察到甲苯磺丁脲试验的这种改善。随着对最初假设的这第二次证实，讨论了老年糖尿病以及一般衰老过程中钾缺乏的发病机制意义和生物学相关性。
