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[孤立性周围神经系统血管炎]

[Isolated vasculitis of the peripheral nervous system].

作者信息

Larrodé P, Ramón y Cajal S, Iñíguez C, Domínguez M, Sanz J M, Morales F

机构信息

Servicio de Neurología, Hospital Clínico Universitario, Zaragoza.

出版信息

Neurologia. 1997 May;12(5):197-9.

PMID:9280427
Abstract

We present a patient with a subacute asymmetrical sensorimotor polyneuropathy. The pathological features were predominantly loss of nerve fibers, axonal degeneration and healed vasculitis. The epineural vessels were involved, while endoneurial capillaires were preserved. Muscle biopsy revealed neurogenic features with normal blood vessels. After three years, motor and sensory function was almost normal, without any specific treatment. No abnormal findings suggesting collagen diseases or other underlying immunological disorders were obtained by various laboratory tests. In conclusion, the present case strongly suggests that the vasculitis was confined to the peripheral nerves.

摘要

我们报告一例患有亚急性非对称性感觉运动性多发性神经病的患者。病理特征主要为神经纤维缺失、轴突变性和愈合的血管炎。神经外膜血管受累,而神经内膜毛细血管保存完好。肌肉活检显示具有正常血管的神经源性特征。三年后,运动和感觉功能几乎正常,未进行任何特殊治疗。各种实验室检查均未发现提示胶原病或其他潜在免疫性疾病的异常结果。总之,本病例强烈提示血管炎局限于周围神经。

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