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[非甾体抗炎药与胃肠道保护:初级保健中的合理处方?]

[Non-steroid anti-inflammatory agents and gastrointestinal protection: adequate prescription in primary care?].

作者信息

Burrull M, Madridejos R, Gregori A, Busquets E

机构信息

ABS Centre y DAP, L'Hospitalet de Llobregat, Barcelona.

出版信息

Aten Primaria. 1996 Nov 30;18(9):507-10.

PMID:9280447
Abstract

OBJECTIVES

To find the frequency of prescription of gastro-intestinal protectors (GIP) at the same time as non-steroidal anti-inflammatory drugs (NSAID). To find certain characteristics linked to their use in primary care. To evaluate how correctly they are prescribed.

DESIGN

A crossover descriptive study.

SETTING

A base urban health area.

PATIENTS

Patients over 14, who attended in 1994, who had a medical history and were treated with NSAID.

MEASUREMENTS AND INTERVENTIONS

1,115 medical histories were obtained by simple randomised sampling, of whom 205 were under treatment with NSAID. A questionnaire was used to evaluate: age, sex, NSAID treatment, GIP, history of peptic ulcer, corticoid or acenocoumarol treatment, tobacco, alcohol and related pathology. After a complete bibliographic review, some criteria were fixed for when it is correct to give GIP-NSAID.

RESULTS

The prevalence of NSAID prescription was 18.39%. 34 patients treated with NSAID received GIP at the same time. Aceclophenac was the most widely prescribed NSAID; and H2 antihistamines, the drugs most commonly used as GIP.

摘要

目的

了解胃肠道保护剂(GIP)与非甾体抗炎药(NSAID)同时开具处方的频率。找出与它们在初级保健中使用相关的某些特征。评估它们的处方开具是否正确。

设计

一项交叉描述性研究。

地点

一个城市基层卫生区。

患者

1994年就诊、有病史且接受NSAID治疗的14岁以上患者。

测量与干预

通过简单随机抽样获取了1115份病史,其中205人正在接受NSAID治疗。使用一份问卷来评估:年龄、性别、NSAID治疗情况、GIP、消化性溃疡病史、皮质类固醇或醋硝香豆素治疗情况、吸烟、饮酒及相关病理情况。经过全面的文献综述后,确定了一些关于何时正确开具GIP - NSAID的标准。

结果

NSAID处方的患病率为18.39%。34名接受NSAID治疗的患者同时接受了GIP。醋氯芬酸是开具最广泛的NSAID;H2抗组胺药是最常用作GIP的药物。

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