Fucci C, Ferrari M, La Canna G, Coletti G, Nardi M, Maisano F, Dalla Tomba M, Alfieri O
II Divisione di Cardiochirurgia, Spedali Civili e Università degli Studi Brescia.
G Ital Cardiol. 1997 Jun;27(6):544-8.
Emerging evidence indicates that etiology plays an essential role in the results of mitral valve repair. In this study, we examined the long-term performance of this procedure in 61 consecutive patients with pure rheumatic mitral insufficiency.
Patient ages ranged from 4 to 74 years (mean: 51.7 +/- 16). Preoperatively, 94% of the patients were in NYHA class II or III.
There was no hospital mortality. According to actuarial methods 94.1% of the patients were alive 7 years postoperatively and 83.3% were reoperation free. Freedom from reoperation was significantly higher in patients who received a prosthetic ring than in those who had other types of annuloplasty (96.7% vs 59.3%; p = 0.001). As opposed to the literature, in our series there was no relationship between valve failure and age at the time of reoperation. There were only two cases of thromboembolism and one of infective endocarditis.
This study confirms that mitral valve reconstruction in rheumatic valve insufficiency can yield satisfactory long-term clinical results, although they are less than optimum compared with those obtained in patients with degenerative disease. Favourable results depend on routine use of a prosthetic ring as well as adequate patient selection. Attention should be focused on improved detection and suppression of rheumatic activity at the time of operation.
新出现的证据表明病因在二尖瓣修复结果中起重要作用。在本研究中,我们检查了连续61例单纯风湿性二尖瓣关闭不全患者接受该手术的长期效果。
患者年龄4至74岁(平均:51.7±16岁)。术前,94%的患者处于纽约心脏协会(NYHA)心功能II级或III级。
无住院死亡病例。根据精算方法,94.1%的患者术后7年存活,83.3%未再次手术。接受人工瓣环的患者再次手术率显著低于接受其他类型瓣环成形术的患者(96.7%对59.3%;p = 0.001)。与文献报道相反,在我们的系列研究中,瓣膜功能衰竭与再次手术时的年龄之间没有关系。仅有2例血栓栓塞病例和1例感染性心内膜炎病例。
本研究证实,风湿性瓣膜关闭不全患者的二尖瓣重建可产生令人满意的长期临床效果,尽管与退行性疾病患者相比效果欠佳。良好的结果取决于人工瓣环的常规使用以及合适的患者选择。应关注手术时改善风湿活动的检测和抑制。