Gottlieb D I, Merrell R, Rock K, Littman D, Santala R, Glaser L
Prog Clin Biol Res. 1977;15:139-46.
Several lines of evidence demonstrate cell-cell receptors on the surface of developing brain cells. Plasma membrane vesicles with regional and temporal binding specificities can be prepared. Active factors that block cell aggregation can be extracted from these membranes and partially purified. Quantitative studies of cell-cell adhesion demonstrate a gradient of adhesive specificity along the dorsoventral axis of the developing retina.
多条证据表明发育中的脑细胞表面存在细胞间受体。可以制备具有区域和时间结合特异性的质膜囊泡。能够从这些膜中提取并部分纯化出阻止细胞聚集的活性因子。对细胞间黏附的定量研究表明，沿发育中视网膜的背腹轴存在黏附特异性梯度。
