Sapp J
Department of Science and Technology Studies, York University, Ontario, Canada.
Hist Philos Life Sci. 1997;19(1):69-87.
Jean Brachet's research on microsomes and the role of RNA in protein synthesis during the 1940s and 50s is placed in the context of embryological views about the role of the cytoplasm in development, and plasmagene theory based on studies of non-Mendelian inheritance in microorganisms. I show how Brachet's subsequent conception of messenger RNA evolved in the context of his conceptions of the relations between plasmagenes and nuclear genes. His theorizing on cytoplasmic organelles and viruses is further situated in the bio-political controversy over the inheritance of acquired characteristics during the Lysenko controversy.
让·布拉谢在20世纪40年代和50年代关于微粒体以及RNA在蛋白质合成中的作用的研究，是在胚胎学关于细胞质在发育中的作用的观点以及基于对微生物非孟德尔遗传研究的细胞质基因理论的背景下进行的。我展示了布拉谢随后关于信使RNA的概念是如何在他对细胞质基因与核基因之间关系的概念背景下演变的。他关于细胞质细胞器和病毒的理论化进一步置于李森科争议期间关于获得性特征遗传的生物政治争议之中。
