Farrell J, Schmitz P G
National Kidney Centre, Beaumont Hospital, Dublin, Ireland.
Clin Nephrol. 1997 Aug;48(2):132-3.
The occurrence of hepatotoxicity and acute renal dysfunction following an acute paracetamol overdose has been well documented. Acute pancreatitis, however, has been rarely described. We would like to report a hemodialysis patient who developed acute pancreatitis and hepatic failure from acute paracetamol toxicity. To our knowledge, this represents the first description in a dialysis patient of paracetamol induced pancreatitis. Given the frequency of paracetamol usage in these patients, we believe that it is important to consider this diagnosis in patients with unexplained acute pancreatitis, particularly if there is associated hepatic dysfunction.
急性对乙酰氨基酚过量服用后发生肝毒性和急性肾功能不全的情况已有充分记录。然而,急性胰腺炎却鲜有报道。我们报告一例血液透析患者,因急性对乙酰氨基酚中毒并发急性胰腺炎和肝衰竭。据我们所知,这是首次在透析患者中描述对乙酰氨基酚诱发的胰腺炎。鉴于这些患者中对乙酰氨基酚的使用频率,我们认为对于不明原因的急性胰腺炎患者,尤其是伴有肝功能不全的患者,考虑这一诊断很重要。