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具有显著淋巴成分的涎腺病变:细针穿刺活检的细胞学表现及鉴别诊断

Salivary gland lesions with a prominent lymphoid component: cytologic findings and differential diagnosis by fine-needle aspiration biopsy.

作者信息

Chai C, Dodd L G, Glasgow B J, Layfield L J

机构信息

Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA.

出版信息

Diagn Cytopathol. 1997 Sep;17(3):183-90. doi: 10.1002/(sici)1097-0339(199709)17:3<183::aid-dc3>3.0.co;2-g.

DOI:10.1002/(sici)1097-0339(199709)17:3<183::aid-dc3>3.0.co;2-g
PMID:9285189
Abstract

Fine-needle aspiration (FNA) is an accepted technique for the preoperative diagnosis of salivary gland nodules. The majority of salivary gland nodules are pleomorphic adenomas and offer little difficulty in diagnosis. Most diagnostically difficult lesions fall into one of four morphologic categories represented by squamous-cell-containing lesions, clear cell neoplasms, neoplasms with a prominence of stromal material, and lymphocyte-containing lesions. Herein, we describe our experience with a series of 61 histologically confirmed cases in which the smears contained a prominent or predominant number of lymphocytes. The differential diagnosis is discussed and points of diagnostic aid enumerated.

摘要

细针穿刺抽吸活检(FNA)是唾液腺结节术前诊断的一种公认技术。大多数唾液腺结节为多形性腺瘤,诊断难度不大。大多数诊断困难的病变可分为四种形态学类型之一,即以含鳞状细胞病变、透明细胞肿瘤、间质物质突出的肿瘤和含淋巴细胞病变为代表。在此,我们描述了我们对一系列61例经组织学证实的病例的经验,这些病例的涂片中有大量或占主导数量的淋巴细胞。文中讨论了鉴别诊断,并列举了诊断要点。

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