使用纵向检测电子自旋共振（LODESR-CT）对大鼠头部腹腔注射氮氧化物自由基进行的计算机断层扫描。

A CT using longitudinally detected ESR (LODESR-CT) of intraperitoneally injected nitroxide radical in a rat's head.

作者信息

Yokoyama H, Sato T, Tsuchihashi N, Ogata T, Ohya-Nishiguchi H, Kamada H

机构信息

Institute for Life Support Technology, Yamagata Technopolis Foundation, Japan.

出版信息

Magn Reson Imaging. 1997;15(6):701-8. doi: 10.1016/s0730-725x(97)82763-4.

DOI:10.1016/s0730-725x(97)82763-4

PMID:9285810

Abstract

We have developed an in vivo longitudinally detected ESR (LODESR) imaging system operating at 700 MHz based on a loop-gap resonator and a pair of saddle-type pickup coils. A good linear relationship between the LODESR signal intensity and the applied power in a range up to 15.8 W was obtained. The detection of LODESR signals was barely affected by variations in the resonant properties. The characteristic of LODESR is suitable for in vivo examination. Using this system, we succeeded in obtaining LODESR-CT images of the head region of a rat after the intraperitoneal injection of a nitroxide radical.

摘要

我们基于环形间隙谐振器和一对鞍型拾波线圈，开发了一种在700 MHz下运行的体内纵向检测电子自旋共振（LODESR）成像系统。在高达15.8 W的范围内，LODESR信号强度与施加功率之间获得了良好的线性关系。LODESR信号的检测几乎不受共振特性变化的影响。LODESR的特性适用于体内检查。使用该系统，我们在腹腔注射氮氧化物自由基后成功获得了大鼠头部区域的LODESR-CT图像。