Yokoyama H, Sato T, Ohya-Nishiguchi H, Kamada H
Institute for Life Support Technology, Yamagata Technopolis Foundation, Japan.
MAGMA. 1998 Dec;7(2):63-8. doi: 10.1007/BF02592230.
In vivo longitudinally detected ESR (LODESR)-CT system operating at 300 MHz was developed, based on the combination of a bridged loop-gap resonator and a pair of saddle-type pickup coils (STPCs). The sensitivity distribution of the STPCs was simulated on the basis of a magnetic dipole model. A LODESR-CT image of a phantom (a physiological saline solution of a nitroxide radical) was satisfactorily corrected by using the simulation result. LODESR-CT images of the head of a rats, in which nitroxide radical was injected intraperitonally, were also obtained through the correction in the same manner. This is the first in vivo CT (i.e. three-dimensional imaging) study with a 300 MHz ESR.
基于桥接环形缝隙谐振器和一对鞍型拾取线圈（STPC）的组合，开发了一种工作在300 MHz的体内纵向检测电子自旋共振（LODESR）-CT系统。基于磁偶极子模型对STPC的灵敏度分布进行了模拟。利用模拟结果对模型（一种含氮氧化物自由基的生理盐水溶液）的LODESR-CT图像进行了令人满意的校正。通过同样的校正方法，还获得了腹腔注射氮氧化物自由基的大鼠头部的LODESR-CT图像。这是首次使用300 MHz电子自旋共振进行的体内CT（即三维成像）研究。
