Martins B I, Raju M R, Hayes T L, Tobias C A
Radiat Environ Biophys. 1977 Oct 12;14(3):243-50. doi: 10.1007/BF01323943.
The colony-forming ability of cultured mammalian cells exposed to monochromatic ultrasonic vibrations of different frequencies (0.1, 0.5, 1.0, 2.0, 3.3 MHz) was studied. The combined effect of x rays and 1.0-MHz ultrasonic waves on the survival of M3-1 cells was also investigated. Split-dose experiments showed that cells exposed to ultrasound are "sensitized" to a subsequent exposure. Almost twice as many cells survive a given ultrasonic dose when exposed in the M phase as when exposed in the S phase. A small amount of synergism between ultrasound and x rays has been observed. The extent of synergism depends on the experimental factors, and may be due to an interaction between nuclear damage caused by x rays and the damage to the cell membrane caused by ultrasound.
研究了暴露于不同频率（0.1、0.5、1.0、2.0、3.3兆赫）单色超声振动下培养的哺乳动物细胞的集落形成能力。还研究了X射线和1.0兆赫超声波对M3 - 1细胞存活的联合作用。分次剂量实验表明，暴露于超声的细胞对随后的暴露“敏感”。当在M期暴露时，给定超声剂量下存活的细胞几乎是在S期暴露时的两倍。已观察到超声与X射线之间存在少量协同作用。协同作用的程度取决于实验因素，可能是由于X射线引起的核损伤与超声引起的细胞膜损伤之间的相互作用。
