Hirvonen T P, Aalto H, Pyykkö I, Juhola M
Department of Otorhinolaryngology, University Central Hospital of Helsinki, Finland.
Acta Otolaryngol Suppl. 1997;529:98-100. doi: 10.3109/00016489709124094.
In the head autorotation test (HART) gain is commonly used to determine the vestibulo-ocular reflex (VOR). The purpose of this work was to evaluate the relevance of phase (the phase difference between the eye and corresponding head movement) in describing the VOR. The phase was determined in 5 frequency bands in both degrees and milliseconds (ms) in 4 groups: 30 healthy adults, 15 elderly subjects, 37 vestibular schwannoma (VS) patients, and 35 Meniere's disease (MD) patients. In healthy adults and in MD patients the phase was close to nil in the frequency bands of 3 and 4 Hz. In elderly subjects phase lead was between 5.0 and 15.5 ms in each frequency band. Patients with VS showed a phase lag of -4.2 to -7.6 ms. The mean phase of the elderly in the frequency band of 3 Hz differed statistically significantly from that of MD and VS patients, and in the frequency band of 4 Hz from that of healthy adults and VS patients. In summary, the elderly had phase lead and VS patients showed increased phase lag in the frequency bands higher than 2 Hz. The phase is useful parameter together with gain in evaluating VOR and it seems to change in aged subjects and in patients with permanent vestibular lesion.
在头部自动旋转试验（HART）中，增益通常用于确定前庭眼反射（VOR）。本研究的目的是评估相位（眼睛与相应头部运动之间的相位差）在描述VOR中的相关性。在4组人群中，分别在5个频段以度和毫秒（ms）为单位测定相位：30名健康成年人、15名老年人、37名前庭神经鞘瘤（VS）患者和35名梅尼埃病（MD）患者。在健康成年人和MD患者中，3Hz和4Hz频段的相位接近零。在老年人中，每个频段的相位超前在5.0至15.5ms之间。VS患者表现出-4.2至-7.6ms的相位滞后。老年人在3Hz频段的平均相位与MD和VS患者的平均相位在统计学上有显著差异，在4Hz频段与健康成年人和VS患者的平均相位有显著差异。总之，老年人在高于2Hz的频段有相位超前，VS患者表现出相位滞后增加。相位与增益一起是评估VOR的有用参数，并且在老年受试者和永久性前庭病变患者中似乎会发生变化。
