Rutter M
Medical Research Council Child Psychiatry Unit, Institute of Psychiatry, London, England.
Can J Psychiatry. 1997 Aug;42(6):569-76. doi: 10.1177/070674379704200602.
To review implications of genetic research in child psychiatry.
Key advances in quantitative and molecular genetics are noted and findings are summarized with respect to autism, attention-deficit hyperactivity disorder, oppositional defiant and conduct disorders, depression, schizophrenia, and Tourette's syndrome.
Genetic findings will be helpful clinically in the elucidation of disordered brain processes, the understanding of nature-nurture interplay, diagnosis, genetic counselling, and pharmacotherapy.
回顾基因研究在儿童精神病学中的意义。
记录数量遗传学和分子遗传学的关键进展,并总结关于自闭症、注意力缺陷多动障碍、对立违抗和品行障碍、抑郁症、精神分裂症以及抽动秽语综合征的研究结果。
基因研究结果在临床上有助于阐明大脑功能紊乱过程、理解先天与后天的相互作用、诊断、遗传咨询以及药物治疗。