Köhnlein S, Brinkmann G, Körner T, Kreusch T, Bohuslavizki K H, Heller M
Klinik für Radiologische Diagnostik, Christian-Albrechts-Universität zu Kiel.
Rofo. 1997 Jul;167(1):52-7. doi: 10.1055/s-2007-1015491.
A prospective study of the value of MRI in the diagnosis of osteomyelitis of the mandible with special reference to the suitability of different MR sequences.
In 13 patients, average age 55 years (12-82), with clinical suspicion of osteomyelitis of the mandible, 18 MRI examinations were carried out (STIR, TSE T2, proton and SE T1 weighted scans with and without contrast, slice thickness 3.5 to 6 mm). Image quality of the sequences was evaluated as well as the suitability of the various sequences for showing the lesion, its location and extent. Activity of the osteomyelitis was judged by the degree of contrast uptake and was correlated with 3-phase bone scintigraphy and with histological findings.
In 9 of the 14 cases the findings on MRI and of the scintigraphy agreed with the histology. In two patients the activity of the inflammatory process was exaggerated by the MRI. In another follow-up examination it was slightly underestimated. All lesions were shown to be highly active by the histology were recognized as such by MRI. For the localisation and recognition of the extent of the inflammatory processes STIR sequences and T1 weighted non-enhanced SE sequences proved the most suitable. Contrast medium is essential to evaluate the inflammatory activity.
MRI is a sensitive diagnostic method; it is as good as 3-phase bone scintigraphy in demonstrating osteomyelitis of the mandible and of its activity but is superior for showing the pathological anatomy.
对MRI在诊断下颌骨骨髓炎中的价值进行前瞻性研究,特别提及不同MR序列的适用性。
对13例平均年龄55岁(12 - 82岁)临床怀疑下颌骨骨髓炎的患者进行了18次MRI检查(STIR、TSE T2、质子加权及SE T1加权扫描,有无增强,层厚3.5至6毫米)。评估了序列的图像质量以及各种序列对显示病变、其位置和范围的适用性。根据对比剂摄取程度判断骨髓炎的活性,并与三相骨闪烁显像及组织学结果进行关联。
14例中的9例,MRI和闪烁显像的结果与组织学相符。2例患者炎症过程的活性在MRI上被夸大。在另一次随访检查中则略有低估。组织学显示所有高活性病变在MRI上均被识别出来。对于炎症过程范围的定位和识别,STIR序列和T1加权非增强SE序列被证明是最合适的。对比剂对于评估炎症活性至关重要。
MRI是一种敏感的诊断方法;在显示下颌骨骨髓炎及其活性方面与三相骨闪烁显像效果相当,但在显示病理解剖方面更具优势。