Aguemon A R, Atchadé D, Houngbé F, Fayomi B
SPAR: Service polyvalent d'anesthésie et de réanimation, CNHU 06, République de Bénin.
Bull Soc Pathol Exot. 1997;90(2):117-9.
Intoxication by pyrimethamine is rare compare to these of patients who ingest a massive dose of amino-4-quinoleine. Clinic manifestations can be delayed and they are specially based on haematologic disorder as shown by literature data. Others organs can be concerned. The authors would like to present the case of a patient with a severe pancytopenia accompanied with: ocular blow like hyperhaemia of conjunctiva then iris siderosis. skin attack as Gũnther's disease. Etiologic treatment by folinic acid is the only deduction. Recovery is complete.
与摄入大量4-氨基喹啉的患者相比，乙胺嘧啶中毒较为罕见。临床表现可能会延迟出现，且如文献数据所示，其特别基于血液系统疾病。其他器官也可能受累。作者想介绍一例严重全血细胞减少症患者的病例，该患者伴有：眼部类似打击伤的结膜充血继而虹膜铁质沉着症；皮肤表现为古特病。亚叶酸的病因治疗是唯一的推断。患者完全康复。
