Czekierdowski A, Zrubek H, Sikorski M, Wiktor H, Józefczak M, Stachowicz N
I Kliniki Ginekologii Operacyjnej AM w Lublinie.
Ginekol Pol. 1996 Nov;67(11):552-6.
The objective of our study was to evaluate the predictive value of serum CA-125 levels and transvaginal ultrasound with color Doppler flow mapping (RI) in patients with benign and malignant ovarian tumors. The retrospective analysis included 78 women in whom 92 tumors were detected. Eleven patients had ovarian carcinoma (a total of 16 tumors). Predictive values were compared for tumor morphology, lowest resistive index (RI) < 0.40 and CA-125 > 35 IU/ml. Sensitivity, specificity, positive and negative predictive values in differentiating malignancy were highest for RI (94%, 87% 87% and 94%, respectively). Morphological criteria or CA-125 levels alone had lower predictive accuracy. Combining of the correctly identified all of the malignancies. It is concluded that preoperative transvaginal ultrasound with color Doppler flow mapping is valuable tool in the assessment of adnexal tumors and can be of assistance in prediction of ovarian cancer.
我们研究的目的是评估血清CA - 125水平以及经阴道超声联合彩色多普勒血流成像（阻力指数）对卵巢良恶性肿瘤患者的预测价值。回顾性分析纳入了78名女性，共检测到92个肿瘤。11名患者患有卵巢癌（共16个肿瘤）。比较了肿瘤形态、最低阻力指数（RI）< 0.40和CA - 125 > 35 IU/ml的预测价值。在鉴别恶性肿瘤方面，RI的敏感性、特异性、阳性预测值和阴性预测值最高（分别为94%、87%、87%和94%）。单独的形态学标准或CA - 125水平预测准确性较低。联合使用可正确识别所有恶性肿瘤。结论是术前经阴道超声联合彩色多普勒血流成像在附件肿瘤评估中是有价值的工具，有助于预测卵巢癌。
