[用于显示冬眠心肌的18氟脱氧葡萄糖单光子发射计算机断层扫描：中期报告]
[18Fluoro-FDG SPECT for the demonstration of hibernating myocardium: an interim account].
作者信息
Alexander C, Schaefer A, Trampert L, Oberhausen E, Kirsch C M, Berberich R
机构信息
Abteilung für Nuklearmedizin Universitätskliniken des Saarlandes, Homburg, Deutschland.
出版信息
Nuklearmedizin. 1997 Jun;36(4):125-30.
AIM
The present investigation demonstrates an intraindividual comparison of FDG-PET and FDG-SPECT.
MATERIAL AND METHODS
Thirty patients with CHD and planed revascularisation underwent both modalities. Myocardial perfusion was evaluated by 99mTc-MIBI SPECT. The myocardium was divided into 25 segments and the results were compared by two experienced observers.
RESULTS
Segmental concordance of FDG-PET and -SPECT was 94.1%. PET indicated a higher percentage of hibernating myocardium (8.9% vs. 5.7%) and a lower rate of matched defects (11.5% vs. 16.0%). In 22 cases the need for revascularisation was assessed identically. In the remaining 8 patients FDG-PET and FDG-SPECT required an intervention in 6 and 2 cases, respectively.
CONCLUSION
The results of FDG-PET and FDG-SPECT showed a high segmental concordance, but the individual assessment of hibernation worthwhile for revascularisation demonstrated important differences in patient management.
目的
本研究展示了氟代脱氧葡萄糖正电子发射断层扫描（FDG-PET）与氟代脱氧葡萄糖单光子发射计算机断层扫描（FDG-SPECT）的个体内比较。
材料与方法
30例患有冠心病且计划进行血运重建的患者接受了这两种检查方式。通过99m锝-甲氧基异丁基异腈单光子发射计算机断层扫描（99mTc-MIBI SPECT）评估心肌灌注情况。将心肌分为25个节段，由两名经验丰富的观察者对结果进行比较。
结果
FDG-PET与FDG-SPECT的节段一致性为94.1%。PET显示冬眠心肌的比例更高（8.9%对5.7%），匹配缺损率更低（11.5%对16.0%）。在22例病例中，对血运重建需求的评估是一致的。在其余8例患者中，FDG-PET和FDG-SPECT分别在6例和2例中提示需要进行干预。
结论
FDG-PET和FDG-SPECT的结果显示出较高的节段一致性，但对于值得进行血运重建的冬眠心肌的个体评估在患者管理方面显示出重要差异。
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