Gorobets E S, Sviridova S P, Gromova E G, Lobanova E D, Mazurina O G, Pleskov A P, Sytov A V
Anesteziol Reanimatol. 1997 May-Jun(3):30-3.
Forty-seven cases with grave sepsis and multiple organ failure in patients operated on for malignant tumors of different localizations and treated in intensive care wards of Cancer Research Center in 1996 are analyzed. In 35 patients sepsis developed due to pyoseptic complications of surgery and led to multiple organ failure, in 12 sepsis complicated multiple organ failure of other origin. Four or five organ systems were involved in 2/3 of patients with "primary" sepsis and in almost all patients with "secondary" sepsis. Sepsis and multiple organ failure in surgical cancer patients are believed to differ much from those in general surgical patients, which is explained by the scope of intervention, a tendency to decrease the number of indications for surgery, and by profound impairment of immunity and metabolism.
对1996年在癌症研究中心重症监护病房接受手术治疗的不同部位恶性肿瘤患者中47例严重脓毒症和多器官功能衰竭病例进行了分析。35例患者因手术脓性并发症发生脓毒症并导致多器官功能衰竭，12例脓毒症并发其他原因引起的多器官功能衰竭。2/3的“原发性”脓毒症患者和几乎所有“继发性”脓毒症患者涉及四或五个器官系统。外科癌症患者的脓毒症和多器官功能衰竭被认为与普通外科患者有很大不同，这是由干预范围、手术指征数量减少的趋势以及免疫和代谢的严重受损所解释的。
