Matuschek M, Sahm K, Bahl H
Institut für Mikrobiologie, Georg-August-Universität Göttingen, Grisebachstr. 8, D-37077 Göttingen, Germany.
Curr Microbiol. 1997 Oct;35(4):237-9. doi: 10.1007/s002849900245.
The nucleotide sequence of two open reading frames (ORFs) from Thermoanaerobacterium thermosulfurigenes EM1 was determined that encode proteins with similarity to components of ATP-binding cassette (ABC) transport systems. Sequence analysis suggests that the deduced proteins AbcA and AbcB consist of an NH2-terminal membrane-spanning domain and a COOH-terminal ATP-binding domain. The deduced proteins AbcA and AbcB showed highest similarity to proteins of the MsbA subfamily of ABC transporters. AbcA and AbcB probably function as a heterodimer. An ORF predicted to encode the primary sigma factor SigA was identified downstream of abcB.
