Feve J R, Mussini J M, Mathé J F, Cler J M, Nomballais M F
Rev Neurol (Paris). 1977 Apr;133(4):271-8.
The authors have reported the case of a 65 year old woman followed for almost 4 years with an akineticrigid Parkinsonian syndrome which responded well to levodopa. Waning of response finally occurred and despite the addition of a peripheral dopa decarboxylase inhibitor the patient died suddenly. Autopsy examination revealed pure nigro-striatal degeneration without any additional pathology. The report deals primarily with purity of the Parkinsonian picture and especially with the conspicuous and prolonged effect of levodopa.
作者报告了一例65岁女性患者，患有运动不能-强直型帕金森综合征，病程近4年，对左旋多巴反应良好。最终反应逐渐减弱，尽管加用了外周多巴脱羧酶抑制剂，患者仍突然死亡。尸检显示为单纯黑质-纹状体变性，无其他病变。该报告主要探讨帕金森病表现的纯粹性，尤其是左旋多巴显著且持久的疗效。
