妊娠合并特发性血小板减少性紫癜采用大剂量脉冲式口服地塞米松治疗。

Idiopathic thrombocytopenic purpura in pregnancy treated with pulsed high-dose oral dexamethasone.

作者信息

Byrne J D, Incerpi M H, Goodwin T M

机构信息

Department of Obstetrics and Gynecology, University of Southern California School of Medicine, Los Angeles, USA.

出版信息

Am J Obstet Gynecol. 1997 Aug;177(2):468-9. doi: 10.1016/s0002-9378(97)70221-7.

DOI:10.1016/s0002-9378(97)70221-7

PMID:9290474

Abstract

Idiopathic thrombocytopenic purpura in pregnancy is usually treated with prednisone or intravenous immune globulin. Because of the fetal risk, there are few good alternatives for women who do not respond. We report a case of refractory idiopathic thrombocytopenic purpura successfully treated with pulsed high-dose oral dexamethasone, which offered ease of administration, low cost, and low risk.

摘要

妊娠期特发性血小板减少性紫癜通常用泼尼松或静脉注射免疫球蛋白治疗。由于存在胎儿风险，对于无反应的女性几乎没有好的替代治疗方法。我们报告一例难治性特发性血小板减少性紫癜患者，采用大剂量脉冲口服地塞米松成功治疗，该方法给药方便、成本低且风险小。