Calvet X, Baigorri F, Duarte M, Joseph D, Saura P, Mas A, Royo C, Artigas A
Internal Medicine Department, Hospital de Sabadell, Barcelona, Spain.
Intensive Care Med. 1997 Jul;23(7):738-42. doi: 10.1007/s001340050402.
To determine whether sucralfate administration affects the tonometric measurement of gastric intramucosal pH (pHi).
Non-randomized observational study.
General intensive care unit of a teaching hospital.
Twenty critically ill, mechanically ventilated, consecutively admitted patients requiring an arterial catheter and nasogastric tube.
Tonometer placement and sucralfate administration.
We simultaneously determined tonometer saline PCO2 (PCO2i), arterial blood gases, pH of gastric juice and pHi. These parameters were evaluated immediately before sucralfate administration, and 2 h and 4 h after. We did not detect any change in either PCO2i or pHi after sucralfate administration (PCO2i: basal 6.4 +/- 1.7, 2 h 6.3 +/- 1.7, 4 h 6.3 +/- 1.7; pHi: basal 7.35 +/- 0.13, 2 h 7.36 +/- 0.12, 4 h 7.36 +/- 0.12).
Sucralfate does not affect the tonometric measurement of PCO2i and pHi.
确定给予硫糖铝是否会影响胃黏膜内pH值（pHi）的张力测定。
非随机观察性研究。
一家教学医院的综合重症监护病房。
20例连续收治的危重症机械通气患者，均需要动脉导管和鼻胃管。
放置张力计并给予硫糖铝。
我们同时测定了张力计盐水PCO2（PCO2i）、动脉血气、胃液pH值和pHi。在给予硫糖铝之前、之后2小时和4小时对这些参数进行评估。给予硫糖铝后，我们未检测到PCO2i或pHi有任何变化（PCO2i：基础值6.4±1.7，2小时6.3±1.7，4小时6.3±1.7；pHi：基础值7.35±0.13，2小时7.36±0.12，4小时7.36±0.12）。
硫糖铝不影响PCO2i和pHi的张力测定。
