Lobetti R G, Miller D B, Dippenaar T
Department of Medicine, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
J S Afr Vet Assoc. 1997 Jun;68(2):66-8. doi: 10.4102/jsava.v68i2.873.
A 3-year-old male German shepherd dog was presented with severe generalised seizures. The dog was protein-intolerant and showed severe hyperammonaemia on ammonia stimulation. The hyperammonaemic state was present for at least 6 weeks and then spontaneously resolved. No obvious cause (liver disease, portocaval shunts, urea cycle enzyme deficiencies, drug therapy or urinary tract obstruction) could be identified. It is possible that this dog had a variation of transient hyperammonaemic syndrome, described in man and recently in a juvenile Irish wolfhound, that extended into adulthood.
一只3岁的雄性德国牧羊犬出现严重的全身性癫痫发作。这只狗对蛋白质不耐受,在氨刺激下表现出严重的高氨血症。高氨血症状态持续了至少6周,然后自行缓解。未发现明显病因(肝病、门腔分流、尿素循环酶缺乏、药物治疗或尿路梗阻)。这只狗有可能患有短暂性高氨血症综合征的一种变体,这种综合征在人类以及最近在一只幼年爱尔兰猎狼犬中有所描述,且在这只德国牧羊犬中持续到了成年期。