Gonvers J J, Henchoz L, Hofstetter J R, Muller W A
Schweiz Med Wochenschr. 1977 Dec 10;107(49):1841-2.
Diabetes in idiopathic hemochromatosis has been considered to be secondary to islet cell damage resulting from the iron deposits. Plasma glucagon was measured by immunoassay using the pancreas specific 30-K antiserum, and was found to be normal or slightly elevated during arginine-infusion tests in patients exhibiting both hemochromatosis and pathological glucose tolerance. This suggests that diabetes in hemochromatosis is not due to a lesion resulting from the iron deposits. The two affections appear to be merely associated and are possibly genetically linked.
特发性血色素沉着症中的糖尿病被认为继发于铁沉积导致的胰岛细胞损伤。使用胰腺特异性30-K抗血清通过免疫测定法测量血浆胰高血糖素，发现在同时患有血色素沉着症和病理性糖耐量的患者进行精氨酸输注试验期间，血浆胰高血糖素正常或略有升高。这表明血色素沉着症中的糖尿病并非由铁沉积导致的病变引起。这两种病症似乎只是相关联，并且可能存在基因联系。
